IGF Insulin like Growth Factor

IGF1 is a polypeptide hormone about the same size as insulin and is a member of the "super family," a family of substances identified as growth factors. IGF is a highly anabolic hormone released primarily in the liver with the stimulus of Growth Hormone (GH).

It is responsible for much of the anabolic activity of GH, including nitrogen retention and protein synthesis as well as muscle cell hyperplasia (increase in number of muscle cells), as well as mitogenesis (the growth of new muscle fibers). Its also important to note that GH and IGF-1 are interrelated. As most athletes already know, GH and IGF levels are both elevated dramatically following exercise, and this may be a primary factor in the anabolic effects of weight training.

IGF-1 may be possibly used as an anabolic substitute for GH in many instances. IGF-1 is, therefore, necessary as well as sufficient in muscle growth and has been shown to also be highly anti-catabolic agent as well. As with all anabolic substances, IGF-1s anabolic effects are still limited only by the protein (amino acid) supply within muscle cells. Thus, as you may expect,

IGF Supplements are usually paired with a high protien diet and protein powders.

IGF is a known neuroprotector and neuropromotor and may be of particular interests to athletes, as it may improve their ability to learn new skills and techniques relevant to their sport.